This street was originally known as Factory Row and led to Smithfield by the late 18 century. In a book called Folktown with content from Éamon Phoenix and Sophie Rasmussen they indicate this street was laid out in 1757 and led to Smithfield by 1791. It was named after Richard Berry who according to Patton was a trustee of the Earl of Donegall and is marked as Berry Street on an 1819 map. Again according to Patton, the General Dispensary was set up here in 1792; it was then transferred to a larger premises to become the Belfast Fever Hospital and General Dispensary in 1797. It then moved again to 1799 to West Street. It is included in the list of streets in the Belfast Directory 1831-1832.